Battle of the Oenoparus
144 BCE.
Shown on the map at 36.199°, 36.161°.
The Battle of the Oenoparus took place in 145 BC on the Oenoparus river (the modern Afrin River, Syria) in the adjoining countryside of Antioch on the Orontes, the capital of the Seleucid Empire. It was fought between a coalition of Ptolemaic Egypt led by Ptolemy VI and Seleucids who favored the royal claim of Demetrius II Nicator against Seleucids who favored the claim of Alexander Balas. Both the Seleucid Empire and the Ptolemaic kingdom were diadochi, Greek-ruled successor states established after the conquests of Alexander the Great. The Ptolemaic force won the battle, and Balas's hopes of securing the throne were ended. However, King Ptolemy VI suffered a mortal wound in the battle. Despite the Egyptian forces winning the battle, they too would be driven out of Syria by the now unified Seleucid Empire under Demetrius II, which turned on the leaderless Egyptian force and drove them out of Seleucid territory.
Text from the Wikipedia article Battle of the Oenoparus, licensed CC BY-SA 4.0.