The siege of Bactra was a siege of the Hellenistic period that lasted from 208 to 206 BC. It was a siege of the city of Bactra by the Seleucid Empire after they defeated the Greco-Bactrians at the Battle of the Arius.
The Seleucids besieged the capital of Bactria until concerning news from the west of his dominions and lack of progress against the city led the Seleucid ruler Antiochus III to negotiate a peace treaty with the Bactrian king Euthydemus and lift the siege. It was agreed that Antiochus would recognize Euthydemus as an ally, and he gave one of his daughters as a wife to Demetrius, Euthydemus' heir.
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