Battle of Jaxartes
328 BCE.
Shown on the map at 40.283°, 69.617°.
The Battle of Jaxartes was fought in 329 BC by Alexander the Great and his Hellenic (Greek) army against the Saka at the River Jaxartes, now known as the Syr Darya River. The site of the battle straddles the modern borders of Uzbekistan, Tajikistan, Kyrgyzstan, and Kazakhstan, just south-west of the ancient city of Tashkent (the modern capital of Uzbekistan) and north-east of Khujand (a city in Tajikistan).
Text from the Wikipedia article Battle of Jaxartes, licensed CC BY-SA 4.0.