Battle of the Uxian Defile
330 BCE.
Shown on the map at 32.189°, 48.258°.
The Battle of Uxian Defile was fought by Alexander the Great against the Uxian tribe of the Persian Empire. The battle raged on the mountain range between the key Persian cities of Susa and Persepolis. Persepolis was the ancient capital of the Persian Empire and held a symbolic value among the native Persian population. They believed that if this city were to fall into enemy hands, then, in effect, the whole Persian Empire would fall into the hands of the enemy.
Text from the Wikipedia article Battle of the Uxian Defile, licensed CC BY-SA 4.0.