Siege of Rhodes
1480 CE.
Shown on the map at 36.167°, 28.000°.
The Siege of Rhodes of 1480 was the first and failed attempt by the Ottoman Empire to seize the island stronghold of the Knights of Rhodes from Rhodes, despite about 70,000 troops, they successfully defended the island.
Text from the Wikipedia article Siege of Rhodes (1480), licensed CC BY-SA 4.0.