Battle of Muros Bay
1543 CE.
Shown on the map at 42.750°, -9.000°.
The Battle of Muros Bay (Spanish: Batalla de Muros) took place on 25 July 1543, during the Italian War of 1542–1546, between the French fleet under Jean de Clamorgan, Lord of Soane and the Spanish fleet commanded by Alvaro de Bazan the Elder. This battle is considered to be the first large naval battle in the Atlantic Ocean.
Text from the Wikipedia article Battle of Muros Bay, licensed CC BY-SA 4.0.