Kalinago genocide of 1626
1626 CE.
Shown on the map at 17.303°, -62.788°.
The Kalinago genocide was the genocidal massacre of an estimated 2,000 Kalinago people by English and French settlers on the island of Saint Kitts in 1626.
Text from the Wikipedia article Kalinago genocide of 1626, licensed CC BY-SA 4.0.