The Battle of Mbororé, which occurred on 11 March 1641, was a conflict between the Guaraníes inhabiting the Jesuit Missions and the bandeirantes, Portuguese explorers and slavers based in São Paulo and allied with the Tupíes. The battle is site is near Cerro Mbororé, Panambí, in the province of Misiones, Argentina. The battle ended in a Guarani victory. It took place at the beginning of the Portuguese Restoration War.
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