Oppau explosion
1921 CE.
Shown on the map at 49.518°, 8.418°.
The Oppau explosion occurred on September 21, 1921, when approximately 4,500 tonnes of a mixture of ammonium sulfate and ammonium nitrate fertilizer stored in a tower silo exploded at a BASF plant in Oppau, now part of Ludwigshafen, Germany, killing at least 560 people and injuring about 2,000 more.
Text from the Wikipedia article Oppau explosion, licensed CC BY-SA 4.0.