Battle of Misiche
244 CE.
Shown on the map at 33.364°, 43.797°.
The Battle of Misiche (Greek: Μισιχή), Mesiche, or Massice (Middle Persian: 𐭬𐭱𐭩𐭪 mšyk; Parthian: 𐭌𐭔𐭉𐭊 mšyk) (dated between January 13 and March 14, 244 AD) was fought between the Sasanians and the Romans in Misiche, Mesopotamia.
Text from the Wikipedia article Battle of Misiche, licensed CC BY-SA 4.0.