Anna of Savoy, born Giovanna (1306–1365), was a Byzantine Empress consort, as the second spouse of Andronikos III Palaiologos. She served as regent, with the titles augusta and autokratorissa, during the minority of her son John V Palaiologos from 1341 until 1347, and later ruled Thessalonica autonomously from 1351. In Byzantium, she was known as Anna Palaiologina, owing to her marriage to Andronikos.
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