Mohammad Khan Ustajlu (Persian: محمد خان استاجلو; died 1514) was an Iranian military commander and official from the Turkoman Ustajlu tribe, who served during the reign of Safavid Shah Ismail I (r. 1501–1524). He played a pivotal role in Ismail I's conquests and expansion in Asia Minor and Mesopotamia, and functioned as governor of the Diyarbakr Province from 1506 to 1514. Mohammad Khan was killed while serving as a commander at the Battle of Chaldiran.
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