Francesco II Sforza (4 February 1495 – 1 November 1535) was Duke of Milan from 1521 until his death. He became duke after Emperor Charles V reconquered Milan from the French. He fought at the Battle of Bicocca against the French, but in 1526 joined the League of Cognac with Francis I of France. Surviving a poisoning, he married Christina of Denmark, but died childless. He was the last member of the Sforza family to rule Milan.
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